Sterile compounding with barrier isolation technology.

Sterile compounding in hospital, home care, and ambulatory care settings is undergoing changes. Barrier-isolation technology for the preparation of sterile compounding is becoming available. The regulatory influence of state boards of pharmacy and the Food and Drug Administration (FDA) on maintaining the sterility of parenteral products and that of the Occupational Safety and Healthy Administration (OSHA) on the preparation and handling of the hazardous drugs may result in changes in pharmacies throughout the country.1 These regulatory agencies focus on the facilities and practices used in the preparation of sterile drug products.